At the end of August 2005, ten-year-old Armani is looking forward to her birthday party in the Lower Ninth Ward of New Orleans, where she and her extended family live, but Hurricane Katrina is on the way, bringing destruction and tragedy in its wake.

"The world has fallen in love with Nick Gautier and the Dark-Hunters. Now Nick's saga continues in the next eagerly anticipated volume... Go to school. Get good grades. Stay out of trouble. That's the mandate for most kids. But Nick Gautier isn't the average teenager. He's a boy with a destiny not even he fully understands. And his first mandate is to stay alive while everyone, even his own father, tries to kill him. He's learned to annihilate zombies...

The Strong family is having a reunion in New Orleans, and twelve-year-old Tristan is supposed to be keeping an eye on his younger cousin Terrance when several things happen at once: he sees his archenemy, King Cotton, and a mysterious girl grabs his magic cellphone--her name is Seraphine, and she seems to know everything about Tristan and the god Anansi (currently inhabiting the cellphone), and she has a mission for Tristan, one that is going lead...

When the mysterious first aid kit takes golden retriever Ranger to New Orleans shortly before Hurricane Katrina hits, he finds himself helping Clare Porter and her grandmother, who are waiting for Clare's father at their home in the Lower Ninth Ward--and when the levees break and Clare is separated from Nana, Ranger must somehow get her to the relative safety of the Superdome, and reunite her with her family.